WebThe IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J Exp Med 1995;182: 219-231. WebFeb 5, 2024 · Chemokine C–X–C ligand 10 (CXCL10), also known as interferon-γ-inducible protein 10 (IP-10), exerts biological function mainly through binding to its specific receptor, CXCR3.
CXCL10/IP-10 - PMC - National Center for Biotechnology …
WebApr 12, 2024 · IP-10 recruits macrophages, lymphocyte T cell, natural killer cell and dendritic cells to the site of the infection . In our study, IL-6 and KC were found to have higher levels in the infected ALOX8 −/− mice than in ALOX8 +/+ mice on day 10 after inoculation, which may account for the differences in lung tissue inflammation or recoveries. WebAug 20, 2002 · The structure of IP-10 was solved by NMR spectroscopy and represents the first structure from the class of agonists toward the receptor CXCR3. CXCR3 binding … foghat live wikipedia
IP-10 Promotes Latent HIV Infection in Resting Memory CD4
C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family. See more The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. See more CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such … See more CXCL9, CXCL10 and CXCL11 have proven to be valid biomarkers for the development of heart failure and left ventricular dysfunction, suggesting an underlining pathophysiological relation between levels of these chemokines and the development of … See more • Human C7 genome location and C7 gene details page in the UCSC Genome Browser. • Human CXCL10 genome location and See more The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92 Å. The Protein Data Bank accession codes for the structures of CXCL10 are 1lv9, 1o7y, and 1o80. See more Baseline pre-treatment plasma levels of CXCL10 are elevated in patients chronically infected with hepatitis C virus (HCV) of genotypes 1 or 4 who do not achieve a sustained viral response (SVR) after completion of antiviral therapy. CXCL10 in plasma … See more • Farber JM (March 1997). "Mig and IP-10: CXC chemokines that target lymphocytes". Journal of Leukocyte Biology. 61 (3): 246–57. See more WebJan 15, 2024 · Ensuing studies revealed that IP-10 and Mig are chemotactic cytokinesor chemokines that lack a conserved ELR amino acid motif and contain two conserved Cys residues separated by one random residue (“X”) in their NH2-terminal sequences. They both act on CXCR3, which was originally reported as a selective receptor for these two … WebMar 8, 2024 · IFN-γ-inducible protein 10 (IP-10, CXCL10) is a 10 kDa chemokine secreted from cells stimulated with type I and II interferons (IFNs) and lipopolysaccharide (LPS). … foghat midi third time lucky