Ctgf ligament
WebThe impact of CTGF/CTGF+ASC treatment on tendon cell growth and differentiation. (a-d) Changes in relative abundance of genes involved in cell growth and differentiation in flexor tendons 14 days ... WebJul 29, 2024 · The current study showed that CTGF could promote the recovery of an injured anterior cruciate ligament. It can upregulate mRNA and expression of TGF-β1, COL1, COL2, SOX9, and tissue inhibitor of TIMP-1, and downregulate mRNA and expression of MMP-13, suggesting that the curative effect of CTGF on injured rabbit ligaments is …
Ctgf ligament
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WebPurpose: This study was undertaken to investigate the role of connective tissue growth factor (CTGF) in fibroblast-to-myofibroblast differentiation and fibroblast-mediated … WebJun 3, 2011 · Abstract. Highlights: {yields} CCN2/CTGF localizes to the ligament-to-bone interface, but is not to the midsubstance region of human anterior cruciate ligament (ACL). {yields} Mechanical stretch induces higher increase of CCN2/CTGF gene expression and protein secretion in ACL interface cells compared with ACL midsubstance cells. {yields} …
WebDec 4, 2009 · Since fibrosis is observed in smokers’ gingiva, it was hypothesized that fibrosis was caused by nicotine in the periodontium. Therefore, in this study, we investigated the effects of nicotine on the induction of a profibrotic molecule, connective tissue growth factor (CCN2/CTGF), in human gingival fibroblasts (HGFs) and periodontal ligament … WebSep 17, 2024 · Cell–cell communication is an essential process to respond to biological stimuli and sustain the micro environmental homeostasis of human periodontal ligament stem cells (hPDLSCs). Connective tissue growth factor (CTGF), a critical secreted matrix protein, exhibits significant tasks in regulating the cell-cell and cell-matrix interactions.
Webligament-derived cells Masahiro Asano1,2, Satoshi Kubota1, ... Connective tissue growth factor (CCN2/CTGF) is a cysteine-rich protein with a molecular weight of 36–38 kDa [1-3] and belongs to ... WebJun 6, 2014 · Appropriate mechanical loading during occlusion and mastication play an important role in maintaining the homeostasis of periodontal ligament (PDL) tissue. Connective tissue growth factor (CTGF/CCN2), a matricellular protein, is known to upregulate extracellular matrix production, including collagen in PDL tissue.
WebJun 6, 2012 · CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, …
WebJun 29, 2024 · Objective . This work is aimed at revealing the role and the molecular mechanism of connective tissue growth factor 2 (CTGF) in the osteoblast differentiation … chromium betaWebApr 1, 2015 · Connective tissue growth factor (CTGF) is a downstream mediator of TGF-β. This study explores the effects of EMD and TGF-β1 on CTGF in periodontal ligament (PDL) fibroblasts and their interactions in PDL proliferation and development. Methods: Human PDL cells were stimulated with EMD. To explore the effects of EMD and TGF-β1 … chromium basierte browserWebThe influence of connective tissue growth factor on rabbit ligament injury repair ... Methods: A rabbit ACL injury model was used to study the effect of CTGF on ligament recovery. chromium based edgeWebDec 1, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN family and is a secreted matricellular and multifunctional protein. ... China) and washed 10 times with PBS (pH 7.2) under sterile conditions. Then, the periodontal ligament tissues attached to the middle third of the roots were curetted … chromium based privacy browserWebJul 23, 2024 · The overall impact of ASCs and CTGF on early tendon healing response. The overall healing response was grossly compared among tendons from three repair groups (N = 10 per group): Control (repaired ... chromium based edge browser downloadchromium barWebSep 6, 2024 · Connective tissue growth factor (CTGF) is an important extracellular matrix protein for bone homeostasis and cell differentiation. The purpose of our study was to … chromium based meaning