site stats

Flotillin function

WebMay 28, 2024 · Functions of flotillins include cell signal transduction, cell-cell contact regulation, membrane-cytoskeletal interaction, and clathrin-independent endocytosis ( 16 – 18 ). WebJan 21, 2014 · The function of flotillin microdomains is not fully understood, but they are likely to be important for linking the plasma membrane and the cytoskeleton [10] – [12], for signaling events [13], …

Flotillin 2 - an overview ScienceDirect Topics

WebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and … WebJun 1, 2015 · Here, we explored flotillin-1-mediated regulation of insulin-like growth factor-1 (IGF-1) signaling. Flotillin-1-deficient cells exhibited a reduction in the activation of IGF-1 receptor (IGF-1R), ERK1/2 and Akt pathways, and the transcriptional activation of Elk-1 and the proliferation in response to IGF-1 were reduced in these cells. how does japan manage earthquakes https://deardiarystationery.com

Christian RA Regenbrecht – Wissenschaftlicher Mitarbeiter

WebFlotillin 1 Antibodies Antibodies that detect Flotillin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and ELISA. These antibodies target Flotillin 1 in Human, Mouse, Rat, Non-human primate and Hamster samples. Web8.2 Flotillins. Flotillin-1 and -2 (also called reggie-2 and -1, respectively) are ubiquitously expressed, evolutionary conserved peripherally membrane-associated proteins of approximately 48 kDa. Palmitoylation on cysteine 34 is essential for membrane association of flotillin-1 ( Morrow et al., 2002) and myristoylation of glycine 2 for that of ... WebMay 26, 2014 · The ubiquitous and highly conserved flotillin proteins, flotillin-1 and flotillin-2, have been shown to be involved in various cellular processes such as cell adhesion, signal transduction through receptor tyrosine kinases as well as in cellular trafficking pathways. Due to the fact that flotillins are acylated and form hetero-oligomers, … how does japan prevent earthquakes

Plant flotillins are required for infection by nitrogen-fixing bacteria

Category:Essential role of flotillin-1 palmitoylation in the intracellular ...

Tags:Flotillin function

Flotillin function

Scaffolding microdomains and beyond: the function of reggie/flotillin …

WebJun 1, 2015 · Flotillin-1 (also known as reggie-2) and flotillin-2 (also known as reggie-1) are membrane-associated oligomeric proteins that are ubiquitously expressed ( Lang et al., 1998; Neumann-Giesen et al., 2004; Solis et al., 2007; Stuermer et al., 2001 ). WebAug 1, 2024 · Flotillin-1 and -2 are markers of membrane rafts but their true endothelial function is unknown. We hypothesized that flotillins are required for TLR signaling in …

Flotillin function

Did you know?

WebDec 31, 2013 · Flotillin-1 and flotillin-2 are two homologous, membrane raft associated proteins. Although it has been reported that flotillins are involved in cell adhesion processes and play a role during breast cancer progression, thus making them interesting future therapeutic targets, their precise function has not been well elucidated. The present … WebFlotillin-1 and -2 ... At a Keystone Symposium on Lipid Rafts and Cell Function in 2006, a consensus was reached that the term ‘lipid rafts’ should be changed to ‘membrane rafts’ recognizing the role of raft proteins, and that caveolae should be considered a membrane raft. Another issue which was discussed at that meeting and that has ...

WebDec 1, 2011 · Flotillin 1 and flotillin 2 are membrane-associated proteins that are thought to function in a number of cellular contexts, including signalling, endocytosis and interactions with the cytoskeleton. Despite being found almost ubiquitously across the … WebAnother flotillin role is to facilitate efficient protein complex assembly, which is probably why flotillin perturbation affects the function of FMM-associated signal transduction …

WebNov 27, 2009 · These results imply that flotillins are conserved between plants and animals. The conserved subcellular localization suggests the possibility of conserved function(s). In this work, we employ a reverse genetics approach to investigate the role of the Medicago truncatula flotillin-like gene family (FLOTs) in symbiosis. WebFlotillin-1 and -2 ... At a Keystone Symposium on Lipid Rafts and Cell Function in 2006, a consensus was reached that the term ‘lipid rafts’ should be changed to ‘membrane rafts’ …

WebJul 15, 2024 · “The flotillins seem to have an effect on the physical structure of the membrane, conferring the correct fluidity so other membrane-bound processes can function properly”," Savietto continues. In further research, the researchers hope to find out what is the exact molecular mechanism between the flotillin proteins and membrane fluidity.

WebFlotillin 1 Insights into the Mechanism for Dictating Polarity in Migrating T-Cells. Flotillin-1 and -2 (also called reggie-2 and... Thy-1-Interacting Molecules and Cellular Signaling in … photo of a jack russell terrierWebNational Center for Biotechnology Information photo of a jaguar catWebFeb 19, 2014 · For a review on flotillin functions in general, the reader is referred to two recent review articles [1,2]. The MAP kinase signaling cascade is the canonical … photo of a jetWebJan 1, 2012 · Flotillins are membrane proteins that form microdomains in the plasma membrane of all mammalian cell types studied to date. They span the evolutionary spectrum, with proteins related to flotillins... how does japan view its place in east asiaWebJan 21, 2014 · The function of flotillin microdomains is not fully understood, but they are likely to be important for linking the plasma membrane and the cytoskeleton –, for signaling events , , for regulating … how does japan treat covid infectionWebFlotillin-1 is a protein that in humans is encoded by the FLOT1 gene. Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal … how does japan political system workWebNov 27, 2009 · These results imply that flotillins are conserved between plants and animals. The conserved subcellular localization suggests the possibility of conserved function(s). … photo of a jack rabbit