WebMay 28, 2024 · Functions of flotillins include cell signal transduction, cell-cell contact regulation, membrane-cytoskeletal interaction, and clathrin-independent endocytosis ( 16 – 18 ). WebJan 21, 2014 · The function of flotillin microdomains is not fully understood, but they are likely to be important for linking the plasma membrane and the cytoskeleton [10] – [12], for signaling events [13], …
Flotillin 2 - an overview ScienceDirect Topics
WebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and … WebJun 1, 2015 · Here, we explored flotillin-1-mediated regulation of insulin-like growth factor-1 (IGF-1) signaling. Flotillin-1-deficient cells exhibited a reduction in the activation of IGF-1 receptor (IGF-1R), ERK1/2 and Akt pathways, and the transcriptional activation of Elk-1 and the proliferation in response to IGF-1 were reduced in these cells. how does japan manage earthquakes
Christian RA Regenbrecht – Wissenschaftlicher Mitarbeiter
WebFlotillin 1 Antibodies Antibodies that detect Flotillin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and ELISA. These antibodies target Flotillin 1 in Human, Mouse, Rat, Non-human primate and Hamster samples. Web8.2 Flotillins. Flotillin-1 and -2 (also called reggie-2 and -1, respectively) are ubiquitously expressed, evolutionary conserved peripherally membrane-associated proteins of approximately 48 kDa. Palmitoylation on cysteine 34 is essential for membrane association of flotillin-1 ( Morrow et al., 2002) and myristoylation of glycine 2 for that of ... WebMay 26, 2014 · The ubiquitous and highly conserved flotillin proteins, flotillin-1 and flotillin-2, have been shown to be involved in various cellular processes such as cell adhesion, signal transduction through receptor tyrosine kinases as well as in cellular trafficking pathways. Due to the fact that flotillins are acylated and form hetero-oligomers, … how does japan prevent earthquakes