WebHere we construct several OM-defected halophile Halomonas bluephagenesis strains to investigate the effects of OM on bioproduction. We achieve enhanced chassis properties of H. bluephagenesis based on positive cellular properties among several OM-defected strains. The OM-defected H. bluephagenesis WZY09 demonstrates better adaptation to lower ... WebJun 24, 2024 · Halomonas bluephagenesis, a haloalkaliphilic bacterium and native polyhydroxybutyrate (PHB) producer, is a non-traditional bioproduction chassis for the next generation industrial biotechnology ...

Engineering the permeability of Halomonas bluephagenesis ... - PubMed

WebHalomonas bluephagenesis has been successfully engineered to produce multiple products under open unsterile conditions utilizing costly glucose as the carbon source. It would be … WebJan 14, 2024 · The Halomonas chassis is also successfully engineered to change its morphology from short bars to long fibers and large spheres for convenient gravity separation. This simplifies the bioprocessing. inb bank springfield il wabash

Engineering Halomonas bluephagenesis as a chassis for …

WebMar 26, 2024 · Ectoine was traditionally produced by Halomonas elongata through a "bacterial milking" process, of which the marked feature is using a high-salt medium to stimulate ectoine biosynthesis and then excreting ectoine into a low-salt medium by osmotic shock. The optimal hydroxyectoine production was achieved by optimizing the … WebMar 1, 2024 · H. bluephagenesis was firstly engineered to be a protein secretion chassis. • Pathway tuning achieved the optimal trade-off between expression and secretion. • The … WebHalomonas spp. have demonstrated their advantages as chassis for next-generation industrial biotechnology. Various metabolic engineering and synthetic biology … in an unfriendly way