WebApr 19, 2024 · 个人认为，s1虽然跟其他核糖体蛋白不太一样，例如分子量过大，有些物种中不存在，在小亚基组装的时候也不需要s1的参与，但是作为跟核糖体联系非常紧密的蛋 … WebJul 11, 2024 · 细胞因子信号传导抑制蛋白 1（SOCS 1）研究 【摘要】 细胞因子信号传导抑制蛋白 (suppressor of cytokine signaling, SOCS)家族是一类由细胞产生并反馈性阻断细胞 …

药学院陈立功课题组应邀发表“溶质转运蛋白（SLCs）与肿瘤免疫 …

http://www.ichacha.net/sic1.html Sic1, a protein, is a stoichiometric inhibitor of Cdk1-Clb (B-type cyclins) complexes in the budding yeast Saccharomyces cerevisiae. Because B-type cyclin-Cdk1 complexes are the drivers of S-phase initiation, Sic1 prevents premature S-phase entry. Multisite phosphorylation of Sic1 is thought to time Sic1 … See more In the G1 phase of the cell cycle, Sic1 binds tightly to the Cdc28-Clb complex and inhibits it. Low Cdc28-Clb activity leads to the disassembly of the mitotic spindle, the assembly of the prereplicative complex and initiation of See more Sic1 needs to be phosphorylated at multiple sites for ubiquitination-driven degradation (Fig. 2). The multiple phosphorylations are required for Sic1 to … See more • p27 • CDKN1B See more • Page of Sic1 at yeastgenome.org See more In order to be recognized by Cdc4 of the SCF complex, Sic1 has to be phosphorylated, often by Cyclin-Cdk complexes, at least at 6 of the 9 cdk sites (Fig. 2). Sic1 can also be phosphorylated by other kinases, such as Pho85-Pc11, a kinase which … See more The protein p27Kip1 is a human homologue of Sic1, both having a conserved inhibitory domain, but p27Kip1 inhibits G1 cyclins and not cyclin B. There are several human diseases that are linked to p27Kip1 and other cyclin kinase inhibitors: See more t-shirt clip art no background

肿瘤细胞“修改”MUC1糖基化，介导免疫逃逸 - 搜狐

WebMUC1可使E-钙粘蛋白(E-cadherin)下调表达, 后者是一种钙离子依赖的细胞粘附分子, 介导细胞间的结合, 在肿瘤转移中起抑制作用, E-钙粘蛋白的下调表达是肿瘤细胞 侵袭性增强的步骤 … WebApr 11, 2024 · 經濟日報 記者謝柏宏／即時報導. 普生 （4117） 昨（11）日公告3月合併營收3,032萬元，較上個月成長74％，較去年同期成長31％；今年首季合併營收為0 ... WebJan 29, 2024 · 细胞膜表面定位的Calreticulin（CRT）蛋白是重要吞噬信号，引导抗原提呈细胞识别靶细胞并进行吞噬。通过对STC1相互作用蛋白质谱分析，研究人员发现STC1能够 … t shirt clipartcom